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Träfflista för sökning "WFRF:(Druid Henrik) srt2:(2005-2009);pers:(Bhardwaj Ratan D.);conttype:(refereed)"

Search: WFRF:(Druid Henrik) > (2005-2009) > Bhardwaj Ratan D. > Peer-reviewed

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1.
  • Bergmann, Olaf, et al. (author)
  • Evidence for Cardiomyocyte Renewal in Humans
  • 2009
  • In: Science. - : American Association for the Advancement of Science (AAAS). - 1095-9203 .- 0036-8075. ; 324:5923, s. 98-102
  • Journal article (peer-reviewed)abstract
    • It has been difficult to establish whether we are limited to the heart muscle cells we are born with or if cardiomyocytes are generated also later in life. We have taken advantage of the integration of carbon-14, generated by nuclear bomb tests during the Cold War, into DNA to establish the age of cardiomyocytes in humans. We report that cardiomyocytes renew, with a gradual decrease from 1% turning over annually at the age of 25 to 0.45% at the age of 75. Fewer than 50% of cardiomyocytes are exchanged during a normal life span. The capacity to generate cardiomyocytes in the adult human heart suggests that it may be rational to work toward the development of therapeutic strategies aimed at stimulating this process in cardiac pathologies.
  •  
2.
  • Bergmann, Olaf, et al. (author)
  • Turnover of Human Cardiomyocytes
  • 2008
  • In: Circulation Research. - 0009-7330. ; 103:12, s. 1494-1495
  • Conference paper (peer-reviewed)
  •  
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  • Result 1-2 of 2
Type of publication
journal article (1)
conference paper (1)
Type of content
peer-reviewed  (2)Undo refine
Author/Editor
Jovinge, Stefan (2)
Druid, Henrik (2)
Alkass, Kanar (2)
Buchholz, Bruce A (2)
Bernard, Samuel (2)
Frisen, Jonas (2)
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Bergmann, Olaf (2)
Zdunek, Sofia (2)
Barnabe-Heider, Fani ... (2)
Walsh, Stuart (2)
Zupicich, Joel (2)
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University
Lund University (2)
Karolinska Institutet (2)
Language
English (2)
Research subject (UKÄ/SCB)
Medical and Health Sciences (2)

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